DFHMQ0480 E MQCC=2 MQRC=2195 when starting CICS-WebSphere MQ adapter

LOGDATA shows your MQ address space had an abend 00D7 with RC=00000025 before the DFHMQ0480E message. The abend 00D7 with RC=00000025 is due to the MQ address space going away. Afterwards, whatever tries to communicate with the address space suffers the DFHMQ0480 E error with MQCC 2 MQRC 2195 on cross memory operations.

 SYMPTOM             DESCRIPTION
 -------             -----------            
 PIDS/5752SC1C5      PROGRAM ID: 5752SC1C5 
 RIDS/NUCLEUS#L      LOAD MODULE NAME: NUCLEUS
 RIDS/IEAVEDS0       CSECT NAME: IEAVEDS0 
 AB/S00D7            SYSTEM ABEND CODE: 00D7
 PRCS/00000025       ABEND REASON CODE: 00000025
 REGS/0F1B6          REGISTER/PSW DIFFERENCE FOR R0F: 1B6
 RIDS/IEAVEDSR#R     RECOVERY ROUTINE CSECT NAME: IEAVEDSR
                                                           
 TIME OF ERROR INFORMATION
 PSW: 4404C000 80000000 00000000 00FFE996
 INSTRUCTION LENGTH: 04   INTERRUPT CODE: 0025
 FAILING INSTRUCTION TEXT: 0950B755 0950B99F 0000EB00
 TRANSLATION EXCEPTION ASID:

In this case, IPCS command VERBX MTRACE entered when looking at the system dump shows that the address space (A=) was cancelled:

 hh:mm:ss.xx CANCEL  ,A=
 hh.mm.ss.xx IEE301I             CANCEL COMMAND ACCEPTED
 hh.mm.ss.xx $HASP890 JOB(MQ jobname) 543
             $HASP890 JOB(MQ jobnam) STATUS=(EXECUTING/R001),CLASS=I,
             $HASP890                PRIORITY=3,SYSAFF=(R001),
             $HASP890                HOLD=(NONE), CANCEL=YES
 hh:mm:ss.xx CSQ3201E  ABNORMAL EOT IN PROGRESS FOR 550
             USER=<username> CONNECTION-ID=<MQ jobname>
             THREAD-XREF=000000000000000000000000 JOBNAME=<MQ jobname>
             ASID=<MQ asid> TCB=<xxxxxxxx> <<<this is associated with DFHMQ0480
 hh:mm:ss.xx IEF450I  - ABEND=S222 U0000 REASON=00000000 551

These abends are the result of someone entering a CANCEL command to end the MQ address space.